Chemical Engineer

Job Description – R&D / Iron Complex Development

Position: R&D Executive / Scientist – Iron Complex Development

Department: R&D / Process Development

Experience: 5–7 Years

Qualification: M.Sc. / M.Tech. in Chemistry, Pharmaceutical Chemistry, or related field

Industry: Pharmaceutical / API

Location: Vapi, Gujarat

Job Purpose

We are looking for an experienced R&D professional with hands-on experience in iron complex/API development. The candidate will be responsible for product development, process optimization, troubleshooting, scale-up, and technology transfer of iron-based pharmaceutical products.

Key Responsibilities

• Develop and optimize ferric and ferrous iron complexes and iron-based APIs.
• Work on Iron Sucrose, Iron Polymaltose/Iron Hydroxide Polymaltose, Ferric Carboxymaltose (FCM) and related iron complexes.
• Design and execute laboratory and pilot-scale experiments.
• Optimize reaction parameters including pH, temperature, reaction time, concentration, addition sequence and oxidation/reduction conditions.
• Optimize critical quality attributes such as molecular weight, particle size, PDI, iron content, oxidation state, solubility, stability and purity.
• Troubleshoot issues related to precipitation, aggregation, colour variation, molecular weight, yield and batch-to-batch consistency.
• Interpret analytical results from GPC, particle-size analysis, Zeta potential, iron assay and other characterization techniques.
• Prepare process parameters, batch procedures, development reports and scale-up protocols.
• Support pilot trials, process scale-up, technology transfer and validation batches.
• Evaluate raw materials and their impact on process performance and final product quality.
• Coordinate with QC, QA, Production, Analytical and Engineering teams.
• Identify opportunities for process improvement, yield improvement, cost reduction and quality enhancement.
• Maintain proper laboratory records and technical documentation.

Required Skills

• Strong practical knowledge of iron chemistry and coordination/complex chemistry.
• Hands-on experience in ferric and/or ferrous iron complex development.
• Knowledge of iron oxidation/reduction chemistry.
• Strong understanding of process parameters and their impact on product quality.
• Experience with iron-carbohydrate and iron-polymer complexes.
• Experience in process optimization and scale-up.
• Strong troubleshooting and problem-solving skills.
• Ability to interpret analytical data and correlate process parameters with product quality.
• Good technical documentation and report-writing skills./

Preferred Experience

Candidates with hands-on experience in pharmaceutical/API development of parenteral or injectable iron products will be preferred.

Ideal Candidate

A technically strong R&D professional who can independently handle the complete development cycle:

Experience: 5–7 Years

Qualification: M.Sc. / M.Tech. in Chemistry, Pharmaceutical Chemistry, or related field

Department: R&D / Process Development

Preferred Background: Pharmaceutical / API / Injectable Iron Complex Development

Role Purpose

We are seeking an experienced R&D professional with 5–7 years of hands‑on expertise in the development of iron complexes, particularly ferric and ferrous iron‑based products. The role involves process development, optimization, troubleshooting, scale‑up, and technology transfer.

Key Responsibilities

• Develop and optimize ferric and ferrous iron complexes and related iron‑based products.
• Design and execute laboratory and pilot‑scale experiments for new product development.
• Work on reaction chemistry, complex formation, precipitation, oxidation/reduction, and process parameters.
• Develop processes for iron sucrose, iron polymaltose, ferric carboxymaltose, iron isomaltoside, and other iron‑carbohydrate/polymer complexes.
• Optimize critical quality attributes such as molecular weight, particle size, iron content, solubility, stability, and purity.
• Troubleshoot precipitation, aggregation, yield, and batch consistency issues.
• Document process parameters, batch procedures, development reports, and scale‑up protocols.
• Collaborate with Analytical, QC, QA, Production, and Engineering teams.
• Support pilot trials, process scale‑up, technology transfer, and validation batches.
• Evaluate raw materials and interpret analytical results (GPC, particle size, zeta potential, iron assay, elemental analysis).
• Identify opportunities for process improvement, yield enhancement, and cost reduction.

Required Technical Skills

• Strong knowledge of iron chemistry and coordination/complex chemistry.
• Hands‑on experience in ferric/ferrous iron complex development.
• Understanding of oxidation/reduction chemistry and critical process parameters.
• Experience in process optimization and scale‑up from lab to pilot scale.
• Ability to correlate process parameters with product quality and analytical results.
• Strong troubleshooting and technical documentation skills.

Preferred Experience

Candidates with direct experience in pharmaceutical/API development of parenteral iron products or injectable iron complexes will be highly preferred.

Ideal Candidate

A technically strong R&D professional capable of independently taking an iron‑complex product from lab development → process optimization → pilot trial → scale‑up → technology transfer.